The following courses are offered by Engineering Online, the Distance Education Division of NC State's College of Engineering. The SEMESTER notation indicates past and tentative future scheduling.

CHE 543   Polymer Science and Technology Fall
This course is intended to provide a broad overview of polymer science and engineering. The emphasis will be given on the synthesis and structure of polymeric materials, the crystalline and glassy states, solution and melt properties, phase behavior, mechanical and rheological properties. 3 credit hours

CHE 551   Biochemical Engineering Spring
Biomolecular engineering fundamentals at the molecular, cellular, and tissue level, including enzyme kinetics, genomics, signaling, and tissue patterning. A broad range of applications from protein and RNA engineering, to stem cells and cancer. 3 credit hours

CHE 568   Conventional and Emerging Nanomanufacturing Techniques and Their Applications in Nanosystems Fall
The goal of this course is to introduce students to nanofabrication techniques and the fundamental properties of nanoscale structures. The first part of the course will cover conventional surface patterning techniques with particular attention to photolithography (the keystone process for creating modern electronics) as well as alternative methods such as imprint and soft lithography. The second part of the course will cover the electronic and physical properties of nanostructures. The final part of the course will discuss applications including microfluidics, 3D printing, energy harvesting, and interfacing electronics with biology.  3 credit hours

CHE 577   Advanced Biomanufacturing and Biocatalysis (also offered as BEC 577) Spring
Overview of biomanufacturing using microorganisms (bacteria, yeast, fungi), eukaryotic cells (insect, plant, CHO) and recombinant enzymes focusing on methods used in industry. Course will emphasize media and process design for optimization of heterologous protein expression, metabolic/cell line engineering, metabolomics, protein engineering to alter enzymes and antibodies. Pathway engineering strategies include developing microbes to produce new therapeutic compounds or overproduce primary metabolites, antibiotics, biotherapeutics, therapeutic enzymes, diagnostics, recombinant vaccines, and biopharmaceuticals. Utilization of immobilized biocatalysts, and microbial kinetics are covered. 3 credit hours

CHE 596   Biodiesel Production Technologies Spring
While biodiesel production is, on the surface, simple, there are myriad variations of practice that utilize approaches involving reaction chemistry, equilibrium thermodynamics, solubility, and supercritical phase behavior. This course will rigorously present the dominant reaction chemistries available, including enzyme and solid acid and base catalysis, and discuss technical aspects of reactor design and operation, as well as separation challenges and technology scenarios.

This course will also deal explicitly with the plethora of feedstock available, and the implication of their adoption for long-term environmental and economic sustainability. Agronomic and environmental issues such as crop rotations, food crop replacement, deforestation, as well as other resource allocation issues will be addressed directly. Finally, the potential of technologies that might have a “transformational” impact on biodiesel production (e.g. algae, frost-resistant Jatropha, metabolic engineering of oil-production in bacteria, etc.) will be analyzed from technological as well as social justice perspectives. 3 credit hours

CHE 596   Biological Dynamics from Molecules to Tissues Fall
This specialty course will introduce students to engineering principles, computational models, and quantitative experiments that connect our understanding of biological processes across molecular, cellular, and tissue-level scales of complexity. Biomedical applications include mechanisms of disease progression, design of targeted therapies, and tissue regeneration. Engineering principles discussed will include process control, tissue and cell size constraints, and trade-offs/optimization. Synthesis and analysis of relevant literature and the use of modeling software tools will be prominently featured. 3 credit hours

CHE 596   Chemical Process Simulation Fall
The course will cover the use of some software packages to model chemical and biochemical processes and unit operations in stand-alone and combination modes. Processes to model on both continuous and batch modes include heating/cooling, heat exchange, fluid flow, phase equilibria, flash operations, distillation, absorption/desorption, extraction, chemical reactions, and fermentation. Students will develop the ability to model some of the afore-mentioned processes from first principles using Matlab and Excel-VBA and all other processes using commercial software packages, such as Aspen Plus, UniSim Design, and SuperPro Designer (accessible at Virtual Computing Lab at NCSU through Remote Desktop connection) . Some cost analysis will be covered. 3 credit hours

CHE 596   Colloid Science and Nanoscale Engineering Spring
This course begins with an in-depth coverage of the fundamentals of colloidal interactions between surfaces, particles, surfactants and biomolecules, and their relevance to self-assembly. The theory and practice of particle characterization by scattering methods and their manipulation by external fields are presented. In the second part of the course, emerging colloid-related technologies in microfluidics, micropatterning, bioarrays and nanostructured materials are presented. Newly added material this year will discuss the emerging field of soft robotics. 3 credit hours

CHE 596   Green Chemical Engineering Spring
This course provides the bottom-line thinking required to design greener, safer chemical synthesis and chemical manufacturing processes.  The class focus is to incorporate green chemistry and green engineering principles from the design stage.  It also looks beyond factory processes and follows a life-cycle thinking perspective, given the growing importance of eco- and carbon-footprinting in the current business environment.  The course is useful for: chemists and engineers who want to incorporate sustainability into process design and retrofitting; environment, health and safety professionals whose jobs may include environmental sustainability, eco-footprinting and environmental improvements; and business practitioners who want to understand how to ‘green’ processes from the design stage. 3 credit hours

CHE 596   Introduction to Molecular Simulation Fall
This course will cover the concepts behind molecular simulation methods at the quantum, atomistic, and mesoscale levels, and the practical issues that arise when using them. We will also cover the basics of running simulations in Unix/Linux-based environments, and some of the modern chemoinformatics methods that combine simulation tools with Machine Learning and Metaheuristics methods. The course will contain two tracks: a basic track for people unfamiliar with molecular simulation, and an advanced for people who already work with or do research in molecular modeling. The assignments will be different for both tracks. 3 credit hours

CHE 596   Polymer Rheology and Processing Spring
This introductory course is designed to offer a broad overview of rheological principles. Prior knowledge in the subject is not required and participants from any discipline are welcome. The course content will have three components: general principles, experimental methods, and applications. The last part will focus on specific systems (e.g. suspensions, foams, gels, coatings, etc.). Major experimental techniques will be discussed, and, participants having taken this course will be familiar with the peculiar flow characteristics of complex systems, be able to quantify Non-Newtonian fluids and be able to interpret /design rheological experiments. Unlike traditional engineering courses that focus on mathematical solutions, the emphasis will be on interpreting physical situations, analyzing/examining experimental results and designing/proposing methods and experiments to probe fundamental hypothesis. 3 credit hours

CHE 596   Surface Chemical Reactions Fall
Introduction to the fundamentals of chemical reactions on solid surfaces with applications in heterogeneous catalysis, micro/nanoelectronics and related fields.  Survey of surface characterization methods emphasizing in situ spectroscopic techniques. Case studies of important applications in energy and environmental catalysis. 3 credit hours

CHE 711   Chemical Engineering Process Modeling Fall
Applications of methods for mathematical analysis to formulation and solution of problems in transport phenomena, process dynamics, and chemical reaction engineering. 3 credit hours

CHE 713   Thermodynamics I Fall
In-depth coverage of chemical engineering thermodynamics principles. Application of non-ideal fluid-phase chemical potentials to problems in phase equilibria. Introduction to statistical mechanics and molecular simulation methods, and relations of molecular structure and intermolecular forces to macroscopic thermodynamic properties. 3 credit hours

CHE 715   Fundamentals of Transport Phenomena Spring, Summer
Advanced course in heat and mass transfer and fluid mechanics, including conservation and constitutive equations, scaling and solution methods for handling boundary value problems, and coupling of chemical reaction/adsorption with diffusion and fluid flow. 3 credit hours

CHE 717   Chemical Reaction Engineering Fall
Rates and mechanisms of homogeneous and heterogeneous reactions, with emphasis on interaction of chemical kinetics and transport phenomena. Design, analysis and scale-up of batch and continuous chemical reactors, with emphasis on non-isothermal reactors. 3 credit hours

CHE 761   Polymer Blends and Alloys Fall
Many polymeric systems of commercial relevance consist of multiple polymeric species. As a result, most of these materials are multiphase, in which case the components segregate sufficiently to endow the system with the properties of each component. In this course, we begin with a brief review of some important concepts in polymer thermodynamics and use these concepts to describe equilibrium phase behavior. Methods for calculating, and measuring properties at, equilibrium will be described. Intrinsic limitations on polymer blending will lead to a discussion of physical and chemical methods by which such limitations can be overcome, including emulsification and reactive processing. Another means by which to produce multiphase polymeric materials is through the design of copolymers. This class of materials yields the formation of nanostructures in the same fashion as surfactants, and the ordering phenomena that occur in these systems will be discussed. Thermodynamic models designed to predict the phase behavior of such materials, as well as salient characterization methods (e.g., microscopy and scattering), will be described. Topics related to interfacial characteristics, measurement and modification will likewise be addressed. 3 credit hours

CHE 775   Multi-Scale Modeling of Matter Spring
This is a hands on graduate level course covering current methods for modeling soft matter (polymers, surfactant solutions, colloids, liquid crystals, etc.), nano-structured materials (nanoparticles, nano-composites, nano-porous materials, etc.), and biomolecular systems at the electronic, atomistic, meso-scale and continuum levels. 3 credit hours