CHE 596-601 Biological Dynamics from Molecules to Tissues
 

This specialty course will introduce students to engineering principles, computational models, and quantitative experiments that connect our understanding of biological processes across molecular, cellular, and tissue-level scales of complexity. Biomedical applications include mechanisms of disease progression, design of targeted therapies, and tissue regeneration. Engineering principles discussed will include process control, tissue and cell size constraints, and trade-offs/optimization. Synthesis and analysis of relevant literature and the use of modeling software tools will be prominently featured. 3 credit hours.

 
   

• Prerequisite
 

This course is designed for graduate students in engineering and the sciences; some mathematics background with a course in ordinary differential equations is highly recommended.  Undergraduates who have taken MA 341, Differential Equations and BCH 451, Introduction to Biochemistry (or equivalent courses) may also enroll.


• Course Objectives
 
  • Describe intracellular processes such as receptor dynamics, signal transduction, and gene regulation in quantitative terms.
  • Relate molecular-scale processes to the behavior of individual cells, and cell functional responses to tissue-scale dynamics.
  • Relate quantitative data to mechanistic modeling of biomolecular systems.
  • Identify the engineering principles present in cellular- and tissue-level systems.

• Course Requirements
 

Homework, participation, and an individual project will be assigned. Access to computer use for modeling software is required.


• Textbook
 

No textbook.  Interaction with the primary scientific literature is expected.


• Computer and Internet Requirements
 

NCSU and Engineering Online have recommended minimum specifications for computers. For details, click here.


• Instructor
 

Dr. Gregory Reeves, Assistant Professor
Chemical and Biomolecular Engineering
Engineering Building I (EB1) 2014
Box 7905
NCSU Campus
Raleigh, NC 27695


Phone:
919-513-0652
Email: gtreeves@ncsu.edu
Web Site: https://people.engr.ncsu.edu/gtreeves/

 

Dr. Jason Haugh, Professor
Chemical and Biomolecular Engineering
Partners Building II 3100
NCSU Campus
Raleigh, NC 27695


Phone:
919-513-3851
Email: jason_haugh@ncsu.edu
Web Site: http://people.engr.ncsu.edu/jmhaugh/